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Лекция: Дисплазия тазобедренных суставов новорожденных |
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Лекция: Дисплазия тазобедренных суставов новорожденныхòà íåâïðàâèìèé çâèâèõ; · îö³íêà ñòóïåíÿ ðîçâèòêó ñóãëîáó - ãëèáèíà òà êîíô³ãóðàö³ÿ àöåòàáóëþìó, ðîçâèòîê òà êîíòóð ëàáðóìó 7,15,16,17. Õî÷à â îñíîâ³ ìîðôîìåòðè÷íîãî ìåòîäó Graf12 òà äèíàì³÷íîãî Harcke7 ëåæàòü ð³çí³ ô³ëîñîôñüê³ êîíöåïö³¿, ìåòîäè ìàþòü áàãàòî ñï³ëüíîãî.  ¿õ îñíîâ³ ëåæèòü âèçíà÷åííÿ âçàºìîðîçòàøóâàííÿ ñòðóêòóð êóëüøîâãî ñóãëîáó. Òàê ìåòîä Graf íå ìຠôóíêö³îíàëüíèõ òåñò³â, àëå ðîçâèíåí³ òà ïåðåâ³ðåí³ ÷àñîì ìîæëèâîñò³ îö³íêè ñï³ââ³äíîøåííÿ àíàòîì³÷íèõ ìàðêåð³â. Ìåòîä Harcke - êð³ì îö³íêè ðîçòàøóâàííÿ ãîë³âêè ñòåãíà òà àöåòàáóëþìó â ð³çíèõ àíàòîì³÷íèõ çð³çàõ, ôóíêö³îíàëüí³ òåñòè ñòàá³ëüíîñò³ ñóãëîáó, àëå ìåíøå ìîæëèâîñòåé äëÿ âèçíà÷åííÿ çð³ëîñò³/íåçð³ëîñò³ ñóãëîáó17. Ëîã³÷íî ïðèïóñòèòè çàêîíîì³ðí³ñòü ïîºäíàííÿ âèêîðèñòàííÿ îáîõ ìåòîä³â ïðè äîñë³äæåíí³ ÄÊØ, îñîáëèâî ïðè ïðîâåäåíí³ ñêðèí³íãîâèõ äîñë³äæåíü, ùî ³ áóëî ñï³ëüíî çàïðîïîíîâàíî Graf, Harcke òà Clarcke ó 1993 ðîö³ 19, òàêîæ âèçíà÷åíî ì³í³ìàëüíèé ñòàíäàðòíèé ïðîòîêîë ÓÑ êóëüøîâèõ ñóãëîá³â. Îñíîâí³ ïðèíöèïè ÿêîãî : · Êóëüøîâ³ ñóãëîáè ìóñÿòü äîñë³äæóâàòèñü â ñòàí³ ñïîêîþ òà ç ôóíêö³îíàëüíèìè òåñòàìè; · Äîñë³äæåííÿ âêëþ÷ຠð³çí³ àíàòîì³÷í³ çð³çè; · Äîñë³äæåííÿ âêëþ÷ຠâèçíà÷åííÿ ìîðôîëî㳿 òà ñòàá³ëüíîñò³ ñóãëîá³â. Äèñêóòóþòüñÿ ïèòàííÿ â³äíîñíî ïðîâåäåííÿ óëüòðàñîíîãðàô³÷íîãî ñêðèí³íãó ÄÊØ ó íîâîíàðîäæåíèõ òà éîãî îïòèìàëüíèõ òåðì³í³â. Óëüòðàçâóêîâèé ñêðèí³íã âñ³õ íîâîíàðîäæåíèõ â ïåðø³ 2 òèæí³ æèòòÿ ïðîâîäèòüñÿ â äåÿêèõ êðà¿íàõ ªâðîïè3,14,32,36. Íåçâàæàþ÷è, ùî äîñë³äæåííÿ 3,32 äîêàçóþòü ïåðåâàãè ñîíîãðàô³¿ â ä³àãíîñòèö³ òà êë³í³÷íîìó ìåíåäæåìåíò³ ÄÊØ â ðàííüìó â³ö³, òàêîæ çàóâàæåíî ùî òîòàëüíèé ñêðèí³íã íîâîíàðîäæåíèõ ïðèâîäèòü äî ã³ïåðä³àãíîñòèêè ³ ã³ïåðòåðàﳿ 18,31. Òîòàëüíèé ñêðèí³íã ìຠòðè ñóòòºâ³ íåäîë³êè18: 1) ó áàãàòüîõ ä³òåé ñîíîãðàô³ÿ ïîêàçóº íàÿâí³ñòü íåçíà÷íèõ â³äõèëåíü ÿê ñòàá³ëüíîñò³ òà ðîçâèòêó àöåòàáóëþì³â, ÿê³ çíèêàþòü ï³çí³øå áåç ë³êóâàííÿ; 2) îáñåðâàö³ÿ òà ë³êóâàííÿ öèõ ôàëüñ-ïîçèòèâíèõ âèïàäê³â ÿê ³ çàãàëüíèé ñêðèí³íã íîâîíàðîäæåíèõ ïîòðåáóþòü çíà÷íèõ êîøò³â òà ðåñóðñ³â; 3) äåÿê³ âèïàäêè äèñïëà糿, ÿê³ ðîçâèâàþòüñÿ ï³ñëÿ íåîíàòàëüíîãî ïåð³îäó ìîæóòü áóòè íå ä³àãíîñòîâàí³. ²íøèé ï³äõ³ä äî âèêîðèñòàííÿ ñîíîãðàô³¿ º ñôîêóñóâàííÿ ñåãìåíòó ïîïóëÿö³¿ ç äîñòîâ³ðíî ï³äâèùåíèì ðèçèêîì ÄÊØ 19 (òàáë 1), ùî º ÿâíîþ ïåðåâàãîþ, îñê³ëüêè çíà÷íî çìåíøóºòüñÿ êëüê³ñòü îáñòåæåíèõ ä³òåé, ñïðîùóºòüñÿ ïðîâåäåííÿ òà çíèæóºòüñÿ çàãàëüíà âàðò³ñòü ïðîãðàì. Boere òà Clarke (íåîïóáë³êîâàí³ äàí³) ïåðåâ³ðèëè öþ êîíöåïö³þ íà òåðèòî𳿠Âåëèêîáðèòàí³¿. Àâòîðè ïðîâåëè êë³í³÷íå îáñòåæåííÿ íîâîíàðîäæåíèõ ÿê ïî÷àòêîâèé åòàï ç ïîäàëüøîþ ñîíîãðàô³ºþ ä³òåé ç âèÿâëåíèìè â³äõèëåííÿìè. Íà äîäàòîê, êîæíà äèòèíà ç ôàêòîðàìè ðèçèêó áóëà ñîíîãðàô³÷íî îáñòåæåíà ó â³ö³ 6 òèæí³â. Ñåðåä ïîïóëÿö³¿ ç 23 535 îáñòåæåíèõ ä³òåé 2079 (9%) áóëè ñêåðîâàí³ íà ñîíîãðàô³þ âíàñë³äîê âèùåçãàäàíèõ ôàêòîð³â ðèçèêó. Ñîíîãðàô³ÿ äîêàçàëà ñâîþ åôåêòèâí³ñòü ïåðåä ðóòèííèì êë³í³÷íèì îáñòåæåííÿì, àëå â ïîäàëüøîìó ñïîñòåðåæåíí³ ó 5 ä³òåé (0.02%) ç íîðìàëüíèìè êë³í³÷íèìè äàíèìè òà â³äñóòí³ñòþ ôàêòîð³â ðèçèêó ðîçâèíóëàñü ÄÊØ. Õî÷à ó äåÿêèõ ä³òåé ç ö³º¿ ãðóïè ïðè òîòàëüíîìó ñîíîãðàô³÷íîìó ñêðèí³íãó ïàòîëîã³ÿ ìîãëà áóòè âèÿâëåíà ÷è íåä³àãíîñòîâàíà ç îäíàêîâîþ éìîâ³ðí³ñòþ, ùî ñâ³ä÷èòü ïðî íàÿâí³ñòü â³äñòðî÷åíèõ â ÷àñ³ êë³í³÷íèõ ïðîÿâ³â ÄÊØ 19,31. Íàñòóïíå ïèòàííÿ ïðî òåðì³íè ïðîâåäåííÿ ñêðèí³íãó. Êóëüøîâ³ ñóãëîáè ç ï³äçâèâèõàìè ÷è çâèâèõàìè ìîæóòü ñàìîñò³éíî ñêîðèãóâàòèñü ï³ä ÷àñ ïåðøîãî ì³ñÿöÿ æèòòÿ áåç ë³êóâàííÿ 2 . Ñêðèí³íã, ïðîâåäåíèé ï³ñëÿ íåîíàòàëüíîãî ïåð³îäó äຠçìîãó âèêëþ÷èòè ôàëüñ-ïîçèòèâí³ âèïàäêè àëå íå âèêëþ÷ຠïîìèëîê â ä³àãíîñòèö³ â³äñòðî÷åíî¿ ÄÊØ. Åôåêòèâí³ñòü êîíñåðâàòèâíèõ ìåòîäèê, òàêèõ ÿê øîðè Pavlik, çàëåæèòü â³ä â³êó äèòèíè íà ïî÷àòîê ë³êóâàííÿ 2,27 . Âðàõîâóþ÷è ö³ ì³ðêóâàííÿ íàéîïòèìàëüí³øèì ÷àñîì ïðîâåäåííÿ ñêðèí³íãó âèãëÿäຠâ³ê äèòèíè 4-6 òèæí³â19. Êîëè ïåðø³ êë³í³÷í³ îáñòåæåííÿ âêàçóþòü íà íåñòàá³ëüí³ñòü ñóãëîá³â (Barlow òà Ortolani òåñòè), ñîíîãðàô³ÿ ìóñèòü áóòè ïðîâåäåíà äî 2 òèæí³â â³êó äèòèíè. Ó äåÿêèõ ä³òåé ðåçóëüòàòè Barlow òà Ortolani òåñò³â º äîñòîâ³ðíèìè. Ö³ ä³òè òàêîæ ïîòðåáóþòü ñîíîãðàô³¿. Êîëè íåñòàá³ëüí³ñòü íå âèçíà÷àºòüñÿ, àëå ïðèñóòí³ ³íø³ îçíàêè, íàïð. ñ-ì ëóñêîòó, ïîêàçàíèé ñîíîãðàô³÷íèé êîíòðîëü, àëå íå ðàí³øå 4-6 òèæíÿ â³êó äèòèíè. Íàéá³ëüø òèïîâî, êîëè íåçíà÷íà íåñòàá³ëüí³ñòü âíàñë³äîê ô³ç³îëîã³÷íî¿ íåäîðîçâèíåíîñò³ çíèêຠíà ïðîòÿç³ ïåðøîãî ì³ñÿöÿ æèòòÿ ³ íå ïîòðåáóº ë³êóâàííÿ. Ó âèïàäêàõ, êîëè ñîíîãðàô³ÿ ä³òåé ó â³ö³ äî 4 òèæí³â âêàçóº íà íåçíà÷í³ â³äõèëåííÿ ÿê ñëàáê³ñòü, ï³äçâèâèõ òà ïîì³ðíî âèðàæåíó íåäîðîçâèíåí³ñòü àöåòàáóëþì³â ðåêîìåíäóºòüñÿ ñïîñòåðåæåííÿ áåç ë³êóâàííÿ. Äèíàì³÷íå ñïîñòåðåæåííÿ äîêàçóº çíèêíåííÿ öèõ ïðîÿâ³â ç ÷àñîì 19. ijòè, ÿê³ ìàþòü ôàêòîðè ðèçèêó, àëå êë³í³÷íå îáñòåæåííÿ áåç â³äõèëåíü ïîâèíí³ ïðîõîäèòè ñîíîãðàô³÷íå îáñòåæåííÿ ó â³ö³ 4-6 òèæí³â. Íàâ³òü ïðè íàÿâíîñò³ ïàòîëîã³÷íèõ çì³í ðîçïî÷àòå ó öüîìó â³ö³ ë³êóâàííÿ ãàðàíòóº óñï³õ 1. Âíàñë³äîê îáìåæåííÿ ðåñóðñ³â òà ³íøèõ ôàêòîð³â óëüòðàñîíîãðàô³÷íèé ñêðèí³íã âñ³õ íîâîíàðîäæåíèõ âèçíàºòüñÿ íåäîö³ëüíèì. Òàáëèöÿ 1 Ôàêòîðè ðèçèêó ÄÊØ
ijâ÷àòêà ìàþòü á³ëüøó ÷àñòîòó ÄÊØ, í³æ õëîï÷èêè, àëå âëàñíå ñòàòü íå âèçíà÷åíà ÿê ôàêòîð ðèçèêó. Òàáëèöÿ 2 Àëãîðèòì ñêðèí³íãó ÄÊØ.
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